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HPLC works adhering to The fundamental theory of slim layer chromatography or column chromatography, exactly where it's a stationary stage and a mobile period. The cellular period flows throughout the stationary phase and carries the components from the combination with it.The solvent shipping and delivery system includes a pump to deliver the s

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This reactive epoxide intermediate may possibly respond with amino acid residues of the CYP enzyme to type drug-CYP (drug-protein) adducts (Scheme six, pathway C). The development on the drug-CYP adducts might or might not demonstrate a time-dependent inactivation on the catalytic activity of this CYP enzyme, according to the covalent binding with

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